En studie av 71 patienter där man undersökt sambandet kroniskt trötthetssyndrom/ME och mitokondriell dysfunktion, kommer till följande slutsats (klicka på textstycket för studien i sin helhet):

"Our observations strongly implicate mitochondrial dysfunction as the immediate cause of CFS symptoms. However, we cannot tell whether the damage to mitochondrial function is a primary effect, or a secondary effect to one or more of a number of primary conditions, for example cellular hypoxia, or oxidative stress including excessive peroxynitrite. Mitochondrial dysfunction is also associated with several other diseases and this is not surprising in view of the important role of mitochondria in almost every cell of the body, but this fact appears to have been recognised only in recent years."

Läs mer på samma teori här, dvs att den största enskilda bakomliggande orsaken till kroniskt trötthetssyndrom/ME är en mitokondriell dysfunktion, som leder till energibrist i cellerna - samma teori som ligger bakom Mark Starrs hypotyreos typ 2: Drmyhill.co.uk